There’s a promising new drug being tested to hopefully cure ME/CFS by attacking its theorized root cause. This article on the HealthRising blog goes over the details of the trial, the drug and the theories and science behind it. It is all very exciting. The associated blog posts go over the science in depth, explaining how people with ME/CFS/SEID have their stress systems always on, always producing serotonin. The drug they are testing would be very targeted, specifically at the cells that are pumping out the excess serotonin. So the effect could of the drug could be very quick although unfortunately remaining drug trials will not be. Fingers crossed and best of luck to Cortene!